The 2025 Notre Dame Fighting Irish football schedule will be the 136th season for the program and its 10th season under head coach Marcus Freeman. The Fighting Irish will play their home games at Notre Dame Stadium in Notre Dame, Indiana.
The schedule will consist of 12 regular season games, including six home games and six away games. The Fighting Irish will open the season on Saturday, August 30, 2025, against the Louisville Cardinals at Notre Dame Stadium. The following week, they will travel to Columbus, Ohio, to take on the Ohio State Buckeyes. Notre Dame will then return home to face the Purdue Boilermakers on September 13, 2025.